Currently SmartConnect Real-time triggers will not work with Dynamics 365 if you are using V9.0. The reason for this is that Dynamics 365 v9.0 has a plug-in architecture which is not allowing calls to any port outside of port 80. SmartConnect is typically installed on 5557.
We are working with Microsoft on a timeframe for when they may offer a fix to make calls to other ports or what we can do to make it work. In the meantime you will want to look at using a change datasource (or bulk) to integrate with Dynamics 365 V9.0.
If you are not using Dynamics 365 V9.0, the Real-time triggers will still work.
This is applicable with any release of SmartConnect.
